What Is Hepatitis?

Symptoms, Causes and Treatments

The word hepatitis comes from the Ancient Greek word hepar (root word hepat) meaning 'liver', and the Latin itis meaning inflammation. Hepatitis means injury to the liver with inflammation of the liver cells.

What is the liver?

The liver is the largest gland in the human body. It weighs approximately 3 lb (1.36 kg). It is reddish brown in color and is divided into four lobes of different sizes and lengths. It is also the largest internal organ (the largest organ is the skin). It is below the diaphragm on the right in the thoracic region of the abdomen. Blood reaches the liver through the hepatic artery and the portal vein. The portal vein carries blood containing digested food from the small intestine, while the hepatic artery carries oxygen-rich blood from the aorta.

The liver is made up of thousands of lobules, each lobule consists of many hepatic cells - hepatic cells are the basic metabolic cells of the liver.

The liver has a wide range of functions, including:

• Detoxification (filters harmful substances form the blood, such as alcohol)
• Stores vitamins A, D, K and B12 (also stores minerals)
• Protein synthesis (makes certain amino acids - the building blocks of proteins)
• The production of biochemicals needed for digestion, such as bile
• Maintains proper levels of glucose in the blood
• Produces 80% of your body's cholesterol (cholesterol is vital)
• The storage glycogen (also converts glucose to glycogen)
• Decomposing red blood cells
• Synthesizing plasma protein
• The production of hormones
• Produces urea (the main substance of urine)

Hepatitis can heal on its own with no significant consequence, or it can progress to scarring of the liver. Acute hepatitis lasts under six months, while chronic hepatitis lasts longer.

Most liver damage is caused by 3 hepatitis viruses, called hepatitis A, B and C. However, hepatitis can also be caused by alcohol and some other toxins and infections, as well as from our own autoimmune process (the body attacks itself).

About 250 million people globally are thought to be affected by hepatitis C, while 300 million people are thought to be carriers of hepatitis B.

Not all forms of hepatitis are infectious. Alcohol, medicines, and chemical may be bad for the liver and cause inflammation. A person may have a genetic problem, a metabolic disorder, or an immune related injury. Obesity can be a cause of liver damage which can lead to inflammation. These are known as non-infectious, because they cannot spread form person-to-person.

How many types of hepatitis are there?

There are five main types of hepatitis that are caused by a virus, A, B, C, D, and E - plus types X and G.

• Hepatitis A - this is caused by eating infected food or water. The food or water is infected with a virus called HAV (Hepatitis A Virus). Anal-oral contact during sex can also be a cause. Nearly everyone who develops Hepatitis A makes a full recovery - it does not lead to chronic disease.

• Hepatitis B - this is an STD (sexually transmitted disease). It is caused by the virus HBV (Hepatitis B Virus) and is spread by contact with infected blood, semen, and some other body fluids. You get Hepatitis B by:
• Unprotected sexual intercourse with an infected person (unprotected sex means without using a condom) Using a syringe that was previously used by an infected person (most commonly happens with drug addicts and people who inject steroids).

• Having your skin perforated with unsterilized needles, as might be the case when getting a tattoo, or being accidentally pricked. People who work in health care risk becoming infected by accident in this way. Sharing personal items, such as a toothbrush or razor, with an infected person.
• A baby can become infected through his mother's milk if she is infected.
• Being bitten by someone who is infected.

The liver of a person infected with Hepatitis B swells. The patient can suffer serious liver damage due to infection, resulting in cancer. For some patients the hepatitis becomes chronic (very long-term or lifelong). Donated blood is always tested for Hepatitis B.

• Hepatitis C - Hepatitis C is usually spread through direct contact with the blood of a person who has the disease. It is caused by the virus HCV (Hepatitis C Virus). The liver can swell and become damaged. In hepatitis C, unlike hepatitis B, liver cancer risk is only increased in people with cirrhosis and only 20% of hep C patients get cirrhosis. Feces is never a route of transmission in hepatitis C. Donated blood is also tested for Hepatitis C.

• Hepatitis D - only a person who is already infected with Hepatitis B can become infected with Hepatitis D. It is caused by the virus HDV (Hepatitis D Virus). Infection is through contact with infected blood, unprotected sex, and perforation of the skin with infected needles. The liver of a person with Hepatitis D swells.

• Hepatitis E - a person can become infected by drinking water that contains HEV (Hepatitis E Virus). The liver swells but there is no long-term consequence. Infection is also possible through anal-oral sex.

• Hepatitis X - if a hepatitis cannot be attributed to the viruses of hepatitis A, B, C, D, or E, it is called Hepatitis X. In other words, hepatitis of an unknown virus.

• Hepatitis G - this is a type of hepatitis caused by the Hepatitis G virus (HGV). Usually there are no symptoms. When there are symptoms they are very mild.

What are the signs and symptoms of hepatitis?

Many people with Hepatitis experience either mild symptoms or none at all. Remember that an infected person's feces are always infectious to other people. When symptoms appear, they usually do so about 15 to 180 days after the person has become infected.

The acute phase of hepatitis - symptoms

The initial phase of hepatitis is called the acute phase. The symptoms are like a mild flu, and may include:

• Diarrhea
• Fatigue
• Loss of appetite
• Mild fever
• Muscle or joint aches
• Nausea
• Slight abdominal pain
• Vomiting
• Weight loss

The acute phase is not usually dangerous, unless it develops into the fulminant or rapidly progressing form, which can lead to death.

As the patient gets worse, these symptoms may follow:

• Circulation problems (only toxic/drug-induced hepatitis)
• Dark urine
• Dizziness (only toxic/drug-induced hepatitis)
• Drowsiness (only toxic/drug-induced hepatitis)
• Enlarged spleen (only alcoholic hepatitis)
• Headache (only toxic/drug-induced hepatitis)
• Hives
• Itchy skin
• Light colored feces, the feces may contain pus
• Yellow skin, whites of eyes, tongue (jaundice)

Patient outcomes after the acute phase depend on various factors, especially the type of hepatitis.

What is chronic viral hepatitis?

Patients infected with hepatitis B and hepatitis C can develop chronic hepatitis. Doctors define chronic hepatitis as hepatitis that lasts longer than 6 months. In chronic hepatitis, the viruses live and multiply in the liver for years or decades. For unknown reasons, these patients' immune systems are unable to eradicate the viruses. The viruses cause chronic inflammation of the liver. Chronic hepatitis can lead to the development over time of extensive liver scarring (cirrhosis), liver failure, and liver cancer. Liver failure from chronic hepatitis C infection is the most common reason for liver transplantation in the European countries. Patients with chronic viral hepatitis can transmit the infection to others.

How is viral hepatitis diagnosed?

Diagnosis of viral hepatitis is based on symptoms, physical findings as well as blood tests for liver enzymes, viral antibodies, and viral genetic materials.

Symptoms and physical findings

Diagnosis of acute viral hepatitis often is easy, but diagnosis of chronic hepatitis can be difficult. When a patient reports symptoms of fatigue, nausea, abdominal pain, darkening of urine, and then develops jaundice, the diagnosis of acute viral hepatitis is likely and can be confirmed by blood tests. On the other hand, patients with chronic hepatitis due to hepatitis B and hepatitis C often have no symptoms or only mild nonspecific symptoms such as chronic fatigue. Typically, these patients do not have jaundice until the liver damage is far advanced. Therefore, these patients can remain undiagnosed for years to decades.

Blood tests

There are three types of blood tests for evaluating patients with hepatitis: liver enzymes, antibodies to the hepatitis viruses, and viral proteins or genetic material (viral DNA or RNA).

Liver enzymes. Among the most sensitive and widely used blood tests for evaluating patients with hepatitis are the liver enzymes, called aminotransferases. They include aspartate aminotransferase (AST or SGOT) and alanine aminotransferase (ALT or SGPT). These enzymes normally are contained within liver cells. If the liver is injured (as in viral hepatitis), the liver cells spill the enzymes into the blood, raising the enzyme levels in the blood and signaling that the liver is damaged.

The normal range of values for AST is from 5 to 40 units per liter of serum (the liquid part of the blood). The normal range of values for ALT is from 7 to 56 units per liter of serum. Patients with acute viral hepatitis (for example, due to hepatitis A or hepatitis B) can develop very high AST and ALT levels (sometimes in the thousands of units per liter range). These high AST and ALT levels will become normal in several weeks or months as the patients recover completely from their acute hepatitis. In contrast, patients with chronic hepatitis B and hepatitis C infection typically have only mildly elevated AST and ALT levels, but these abnormalities can last years or decades. Since most patients with chronic hepatitis are asymptomatic (no jaundice or nausea), their mildly abnormal liver enzymes are often unexpectedly encountered on routine blood screening tests during yearly physicals or insurance physicals.

Elevated blood levels of AST and ALT only means that the liver is inflamed, and elevations can be caused by many agents other than hepatitis viruses, such as medications, alcohol, bacteria, fungus, etc. In order to prove that a hepatitis virus is responsible for the elevations, blood must be tested for antibodies to each of the hepatitis viruses as well as for their genetic material.

Viral antibodies. Antibodies are proteins produced by white blood cells that attack invaders such as bacteria and viruses. Antibodies against the hepatitis A, B, and C viruses usually can be detected in the blood within weeks of infection, and the antibodies remain detectable in the blood for decades thereafter. Blood tests for the antibodies can be helpful in diagnosing both acute and chronic viral hepatitis.

In acute viral hepatitis, antibodies not only help to eradicate the virus, but they also protect the patient from future infections by the same virus, that is the patient develops immunity. In chronic hepatitis, however, antibodies and the rest of the immune system are unable to eradicate the virus. The viruses continue to multiply and are released from the liver cells into the blood where their presence can be determined by measuring the viral proteins and genetic material. Therefore in chronic hepatitis, both antibodies to the viruses and viral proteins and genetic material can be detected in the blood.

Examples of tests for viral antibodies are:

• anti-HAV (hepatitis A antibody)
• antibody to hepatitis B core, an antibody directed against the inner core (nucleus) of the virus (core antigen)
• antibody to hepatitis B surface, an antibody directed against the outer surface envelope of the virus (surface antigen)
• antibody to hepatitis B e, an antibody directed against the genetic material of the virus (e antigen)
• hepatitis C antibody-antibody against the C virus

Viral proteins and genetic material. Examples of tests for viral proteins and genetic material are:

• hepatitis B surface antigen
• hepatitis B DNA
• hepatitis B e antigen
• hepatitis C RNA

Other tests. Obstruction of the bile ducts, from either gallstones or cancer, occasionally can mimic acute viral hepatitis. Ultrasound testing can be used to exclude the possibility of gallstones or cancer. For more information, please read the Ultrasound article.

Treatments for hepatitis

• Hepatitis A - There is no treatment specifically in allopathy for hepatitis A. Doctor will advise the patient to abstain from alcohol and drugs during the recovery. The vast majority of patients with Hepatitis A will recover spontaneously. In the herbal therapy “LIVOCLEAN” Tablets is best remedy for Hepatitis A.

• Hepatitis B - A patient with Hepatitis B needs to rest. He will require a diet that is high in protein and carbohydrate - this is to repair damaged liver cells, as well as to protect the liver. If this is not enough, the doctor may prescribe interferon. Interferon is an antiviral agent. Permanent cure in the herbal therapy NFL Introduces a herbal product “LIVOCLEAN” Tablets.

• Hepatitis C - A patient with Hepatitis C will be prescribed pegylated interferon and ribavirin. In the herbal therapy “LIVOCLEAN” Tablets are best remedy for Hepatitis C.

• Hepatitis D or E - So far, there is no effective treatment in allopathy for either Hepatitis D or E but in the herbal therapy “LIVOCLEAN” is best remedy.

• Non-Viral Hepatitis - If the patient has non-viral hepatitis, the doctor needs to remove the harmful substance. It will be flushed out of the stomach by hyperventilation or induced vomiting. Patients with drug-induced hepatitis may be prescribed corticosteroids in allopathy. All non Viral Hepatitis Symptoms cure with “LIVOCLEAN” Suffeciently.

How to prevent hepatitis

How to prevent Hepatitis A

• Wash your hands with soap after going to the toilet
• Only consume food that has just been cooked
• Only drink commercially bottled water, or boiled water if you unsure of local sanitation
• Only eat fruits that you can peel if you are somewhere where sanitation is unreliable
• Only eat raw vegetables if you are sure they have been cleaned/disinfected thoroughly
• Get a vaccine for Hepatitis A if you travel to places where hepatitis may be endemic

How to prevent Hepatitis B

• Tell the partner if you are a carrier or try to find out whether he/she is a carrier
• Practice safe sex
• Only use clean syringes that have not been used by anyone else
• Do not share toothbrushes, razors, or manicure instruments
• Have a Hepatitis B series of shots if you are at risk
• Only allow well sterilized skin perforating equipment (tattoo, acupuncture, etc.)

How to prevent Hepatitis C

• If you are infected do not let others share your toothbrush, razor, manicure equipment
• If you are infected cover open wounds
• Do not share needles, toothbrushes, or manicure equipment
• If your skin is to be pierced, make sure equipment is well sterilized (tattoo, etc.)
• Go easy on the alcohol
• Do not share drug equipment

How to prevent Hepatitis D

• Use the same guidelines as for Hepatitis B. Only a person who is infected with Hepatitis B can become infected with Hepatitis D.

How to prevent Hepatitis E

• Do the same as you would to protect yourself from Hepatitis A infection.

How to prevent Alcoholic Hepatitis

• Go easy on the alcohol, or abstain from consuming alcohol

How to prevent Toxic/Drug Induced Hepatitis

• Make sure you know about the lethal contents of all chemicals
• Make sure the spray is not pointing at you
• Make sure you wear protective gear if you have to